Synthesis of new disoxaril analogues with potent and selective anti-human rhinovirus 14 activity
Massa S., Artico M., Mai A., Ragno R., Corelli F., Pani A., Marongiu M.E., Tramontano E., La Colla P., Bioorganic and Medicinal Chemistry Letters, 1991
Abstract:
New analogues of disoxaril have been synthesized and tested against DNA and RNA viruses. 5-Chloro-2-[4,5-dihydro-2-(oxazolyl)phenoxypropylcarbonyl] [4,5-dihydro-2-(oxazolyl)phenoxypropylcarbonyl]thiophene showed the highest potency and selectivity against HRV-14. © 1991.
Link to the article:
http://dx.doi.org/10.1016/S0960-894X(01)81153-7